| 학회 | 한국공업화학회 |
| 학술대회 | 2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 22권 2호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | In Situ Crosslinked Chitosan/Polyethylene glycol Hybrid Hydrogels(1):Synthesis and Characterization |
| 초록 | Hybrid hydrogels composed of natural and synthetic polymers have been emerged to improve the mechanical and biological properties of hydrogels. In this study, we developed injectable hydrogels composed of chitosan and PEG using horseradish peroxidase(HRP)-catalyzed reaction. The polymers, Chitosan-hydroxylphenyl propionic(CH) and Polyethylene glycol-tyramine(PT) were respectively synthesized and characterized by 1H NMR and UV. The physico-chemical and mechanical properties of hydrogels were investigated by varying the polymer compositions(CH:PT=10:0~0:10 in weight percent). Interestingly, PEG concentration of 5 wt% singnificantly increased the mechanical strength of hybrid hydrogels compared to only CH or PT hydrogels. These results suggest that the mechanical properties of CH/PT hydrogels are adjustable by tuning the polymer composition for a wide range of biomedical application. Acknowledgement:the Materials and Components Technology Development Program of MOTIE/KEIT[10062079] |
| 저자 | 정하영1, 황보경희2, 배진우2, 레티풍1, 박기동1 |
| 소속 | 1Ajou Univ., 2Genoss |
| 키워드 | Injectable hydrogel; Chitosan; Polyethylene glycol |
