화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2005년 봄 (04/14 ~ 04/15, 전경련회관)
권호 30권 1호, p.667
발표분야 의료용 고분자 부문위원회
제목 Preparation and characterization of poly(terephthalate)/silver nanofibrous scaffolds and their antibacterial activities
초록 Nanofibers are the ultra-fine solid fiber notable for their very small diameters. And electrospinning is one of the useful ways to form nanofibers.1 Here we report the preparation of the nanofibrous scaffolds for the biomedical application using electrospinning.
Polyethylene terephthalate (PET) shows the excellent properties like transparency, outstanding processability, light weight, and good impact resistance. Therefore PET is widely used for barriers, fibers, sheets and films. In this study, antibacterial activities of PET was significantly improved by blending with silver nanoparticles. Silver itself can be used as antibacterial and deodorizing agents. And it in recent years has been used in a variety of medical applications.2
PET was dissolved in 1,1,1,3,3,3-Hexafluoro-2-propanol and colloidal silver in isopropyl alcohol was added. PET chips blended with silver nanoparticles were dissolved in 1:1 dichloromethane and trifluoroacetic acid. The solutions were subjected to electrospinning to fabricate nanofiber mats on the PET nonwoven fabrics. The PET/Ag blended nanofiber mats were investigated by XRD, ICP, and ESCA. The morphology of nanofibrous scaffolds was observed using scanning electron microscope (SEM). The antibacterial effect of PET/Ag blended nanofibers on Staphylococcus aures and Klebsiella pneumoniae was performed by the shaking flask and the static vial methods.3
The SEM morphology of PET nanofibers is shown in Fig. 1 and that of PET/Ag nanofibers shown in Fig. 2.


Fig 1. SEM view of PET nanofibers Fig 2. SEM view of PET/Ag nanofibers

Reference
1. A. Frenot and I.S. Chronakis, Current Opinion in Collid & Interface Science, 8, 64-75 (2003)
2. A. J. Betts, D. P. Dowling, M. L. McConnell, and C. Pope, Materials & Design, 26, 217-222 (2005)
3. W.C. Oh and W.C. Jang, Carbon, 41, 1737-1742 (2003)
저자 정경혜1, 강인규1, 허만우2, 배정숙3, 현석희1
소속 1경북대, 2경일대, 3대구대
키워드 nanofiber; PET; silver; antibacterial
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