| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
고분자 합성 |
| 제목 |
Preparation of nanocarrier with amphiphilic polymers for centella asiatica |
| 초록 |
There have been many studies to develope efficient systems for the site specific delivery of drugs using appropriate carrier systems. Therefore we used centella asiatica for drugs and amphiphilic polymers for carrier systems. Amphiphilic polymers composed of methoxy poly(ethylene glycol)s and ε-caprolactone were prepared with a various molar ratio. In order to compare the size of nanocarriers, we synthesized polymers using different molecular weights(2000 and 5000). The products were analyzed by FT-IR spectra and DSC measurements for the thermal behaviour of the copolymers on their composition. The compositions and molecular weights of the products were determined by 1H-NMR spectroscopy and GPC measurement. We confirmed the size and release behavior of liposomes as well. |
| 저자 |
최경화1, 이상봉1, 이창기1, 조계민1, 서동학2, 심진기1
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| 소속 |
1한국생산기술(연), 2한양대 |
| 키워드 |
amphiphilic polymers; centella asiatica; nanocarrier
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| E-Mail |
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