| 학회 |
한국고분자학회 |
| 학술대회 |
2017년 봄 (04/05 ~ 04/07, 대전컨벤션센터) |
| 권호 |
42권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Synthesis of beta-glucan hydrogel containing metronidazole and its antibacterial activity |
| 초록 |
Beta-glucans belong to a group of polysaccharides that are present in the cell walls of bacteria, fungi and so on. They are considered biological response modifiers with immunomodulatory and beneficial health effects, including anticancer properties. In this study, we prepared beta-glucan hydrogel containing drug. Metronidazole (MD) was selected as a drug. MD is frequently used in the treatment for periodontal diseases since it can be against several gram-negative anaerobic rods. The beta-glucan solution was cross-linked with gamma-ray irradiation at room temperature to make hydrogel. The beta-glucan hydrogels was dipped into the MD solution. Their physical properties such as gelation, swelling ratio, compressive strength have been investigated. Also, the antibacterial properties were evaluated by paper diffusion test. |
| 저자 |
박종석, 정진오, 백재, 안성준, 권희정, 정성린, 노영창, 임윤묵
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| 소속 |
한국원자력(연) |
| 키워드 |
Beta-glucan; Hydrogel; Radiation; antibacterial activity
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| E-Mail |
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