| 학회 |
한국공업화학회 |
| 학술대회 |
2014년 가을 (11/12 ~ 11/14, 엑스코(대구)) |
| 권호 |
18권 2호 |
| 발표분야 |
(펄프제지)첨단 펄프제지기술 동향 |
| 제목 |
Cellulose Fibril-Based Hydrogels for Drug Release System |
| 초록 |
Cellulose fibrils such as cellulose nanofibrils (CNF) and cellulose microfibrils (CMF) from hardwood pulp were isolated by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO) mediated oxidation to obtain negatively charged carboxylate on their surfaces that have been used to induce nanogels and microgels through ionic interactions. Characteristics of these two types of hydrogels were analyzed to evaluate their influence to the drug release behavior of the hydrogels. First, morphology, chemical structure, mechanical properties, surface area, and pore size of both nanogels and microgels were characterized by various methods. Both hydrogels prepared by the trivalent cation resulted in the highest stiffness and compressive strength than those of the other hydrogels prepared by mono- or di-valent cations. The nanogels induced by the trivalent cation also showed the highest swelling ratio and the lowest release of the drug. |
| 저자 |
박병대1, Nanang Masruchin1, Valerio Causin2
|
| 소속 |
1경북대, 2Depaertment orf Chemical Sciences / Univ. of Padova |
| 키워드 |
Cellulose fibrils; TEMPO; ionic interaction
|
| E-Mail |
|
