화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 봄 (05/02 ~ 05/04, 대구 엑스코(EXCO))
권호 22권 1호
발표분야 생체재료_포스터
제목 Comparative study of substrate-supported extracellular matrices prepared from various cells for cardiovascular applications
초록 Although vascular stents have been usually treated with narrowed blood vessels, some of these still cause severe problems such as inflammation, restenosis and thrombosis. In our previous study, we developed surface coating of extracellular matrices by employing sequential treatments of polydopamine (pDA) and fibronectin (FN) for the modification of vascular stents. However, components of the substrate-anchored matrices have not been still identified. Using genetic and proteomic analyses, various cells derived ECMs was comparatively investigated to investigate cell-dependent effects on a specific cell. Our results demonstrate that our matrix coating method is sufficiently available for biomedical applications.
저자 김윤아1, 정미진1, 김익환2, 박광숙1, 한동근3, 정윤기1
소속 1한국과학기술(연), 2고려대, 3차의과학대
키워드 pDA; FN; cardiovascullar application
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