| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
A Versatile Approach to Direct Extracellular Matrix Coating Using Polydopamine and Fibronectin for Biomedical Devices |
| 초록 |
Implantable biomedical devices have been widely used for the treatment of diseases and even attracted much attention for wearable devices such as implantable sensors and electronics. However, those have caused severe problems because of poor compatibility in biointerface. To overcome this, we employed a sequential coating of polydopamine (pDA) and fibronectin (FN) on a metal surface (CoCr). The surface-modified CoCr was characterized by SEM, AFM, FTIR and XPS, and was applied to coat extracellular matrix (ECM) through decellularization. We also diversified the cell sources of coated ECM and compared each other using genetic and proteomic analysis tools. It is believed that the versatile sequential coating with pDA and FN will be not only a promising approach but also provide the information for the wide range of future applications in tissue regeneration. |
| 저자 |
정미진1, 박광숙1, 김익환2, 한동근1, 정윤기1
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| 소속 |
1한국과학기술(연), 2고려대 |
| 키워드 |
cobalt-chromium; polydopamine; fibronectin; decellularization; extracellular matrix
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| E-Mail |
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