화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2017년 가을 (10/11 ~ 10/13, 제주컨벤션센터)
권호 42권 2호
발표분야 고분자가공/복합재료
제목 Preparation and Characterization of Poly(ε-caprolactone) Microcapsule Containing Chamaecyparis obtusa oil
초록 Microcapsules could be used in cosmetics, pharmaceutical, quasi drugs and medical applications. Poly(ϵ-caprolactone) (PCL), a biodegradable, biocompatible polymer and nontoxicity, is useful to encapsulate a wide range of drugs making it material for the preparation of carriers with potential applications in therapeutics. Poly(ϵ-caprolactone) microcapusules containing Chamaecyparis obtusa oil utilizing supercritical fluid extraction were prepared by solvent evaporation method. Poly(vinyl alcohol) was used as a emulsifier and dichloromethane was used as a solvent for PCL and Chamaecyparis obtusa oil. Image analyzer and scanning electron microscope (SEM) were used to observe the shape and surface of microcapsule. Thermal behaviors were studied by using a differential scanning calorimetry (DSC). PCL microcapsules containing drugs were confirmed using FT-IR spectra. The drug release test of PCL microcapsules was characterized by UV/vis. spectra.
저자 장영수, 문명재, 이원준, 이수진, 김윤재, 정혜진, 구재환
소속 (재)전남생물산업진흥원 나노바이오연구센터
키워드 Microcapsule; Poly(ϵ-caprolactone); Chamaecyparis obtusa oil; supercritical fluid extraction
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