| 학회 |
한국공업화학회 |
| 학술대회 |
2007년 가을 (11/02 ~ 11/03, 한경대학교) |
| 권호 |
11권 2호 |
| 발표분야 |
정밀화학 |
| 제목 |
항균제 O-(QUINOLONE-3-CARBOXYL)키토산 유도체의 합성 |
| 초록 |
Some alkyl-chitosan derivatives which have improved antibacterial and antifungal activities, such as amino group contained O-acyl chitosan at C-6 are promising agents for drug application aiming its use as medical case. Some quinolone bearing a fluorine atom at C-6 and N-alkyl group at N-1, known as fluoroquinolones are among the most important antimicrobial agents, showing both a high potency and a broad antibacterial spectrum. In this work, O-quinolone substituted chitosan derivatives with a degree of substitution of N-benzyllquinolone carboxylic acid derivatives with chitosan in the presence of acidic condition as a catalyst. The resulting substituted chitin and chitosan was characterized by phsical properties. |
| 저자 |
류성렬1, 장향동2, 류가연3, 안병제4
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| 소속 |
1대불대, 2서울산업대, 3이화여자대, 4동국대 |
| 키워드 |
quinolone-chlitosan; antibacterial chitosan; chitosan drug
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| E-Mail |
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