| 학회 | 한국화학공학회 |
| 학술대회 | 2011년 가을 (10/26 ~ 10/28, 송도컨벤시아) |
| 권호 | 17권 2호, p.1464 |
| 발표분야 | 생물화공 |
| 제목 | The effect of magnetic force on cell viability |
| 초록 | Magnetic Nanoparticles(MNPs) with an average diameter of 79nm were synthesized via thermal decomposition of iron(Ⅲ) acetylacetonate in a mixture composed of oleic acid and benzyl ether. Obtained MNPs were prepared by coating polyethlene glycol-phospholipid onto ferrimagneric iron oxide nanocubes. The experiments were performed to identify the differences between the cell's states in a magnetic field before and after the treatment on the macrophage THP-1 with MNPs. The experiment data was achieved by changing the concentration, magnetic force, and time of magnetic force exposure.Consequently, the cell vitality tends to be decreased at higher concentration of particles, stronger magnetic force, and longer exposure time to magnetic force. Also, up to 10ug/mL of particle concentration, less than 10% of total cell number was decreased and decreasing less than 10% is considered as acceptable range of decrease.However, if the particle concentration is higher than 25ug/mL the vitality of cells tends to be deceased gradually by increasing the cell concentration. |
| 저자 | 우 진1, 김세화2, 문대원2, 안동준1 |
| 소속 | 1고려대, 2한국표준과학(연) |
| 키워드 | Cell; Viability; Magnetic Nanoparticle |
| 원문파일 | 초록 보기 |
