| 학회 | 한국고분자학회 |
| 학술대회 | 2003년 가을 (10/10 ~ 10/11, 부경대학교) |
| 권호 | 28권 2호, p.102 |
| 발표분야 | 고분자 합성 |
| 제목 | A Study on the Synthesis and Characterization of Novel Water-Soluble Polymer-Polymer Complex using Chitosan and PEG-monosuccinate |
| 초록 | ABSTRACT Chitosan (β-1,4-D-glucosamine), a polysaccharide with excellent biological properties, has been widely used in biomedical fields, but many barriers still exist to its broader usage due to its chemical and physical limitations. Further work is needed to improve these properties, but changes of the chemical and physical properties will influence its biocompatibility, so the biological attribute of modified chitosan must be evaluated. In this study, water-soluble polymer complex prepared from chitosan and poly(ethylene glycol)(PEG)-monosuccinate was established by two-step reaction. PEG-monosuccinate was synthesized by one to one mol ratio of PEG and succinic anhydride. then, novel water-soluble chitosan-polymer complex was prepared. The chemical structure of polymer complex synthesized from chitosan and PEG-monosuccinate was analyzed through the elemental analysis(EA), FT-IR, 1H NMR and 13C NMR. The result, it was found that the observed EA, FT-IR, 1H NMR and 13C NMR data were good agreement with the new polymer complex. Also, chitosan-polymer complex after synthesized shows excellent solubility in the water. |
| 저자 | 김대선, 손태원, 정민기, 김영훈, 최용혁 |
| 소속 | 영남대 |
| 키워드 | chitosan; complex; PEG-monosuccinate; succinic anhydride |
