화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2015년 봄 (04/22 ~ 04/24, 제주 ICC)
권호 21권 1호, p.420
발표분야 생물화공
제목 High level conversion of L-lysine into cadaverine by recombinant Escherichia coli whole cell biocatalyst
초록 L-lysine is a promissing feedstock for the synthesis of various platform chemicals such as cadaverine, 5-aminovaleric acid, glutaric acid and caprolactam. Among these chemicals, cadaverine that can be synthesized by a one-step enzymatic reaction of lysine decarboxylase (LDC) from L-lysine, has drawn much attention for its commercial application since it can be used as a monomer of nylon 5, 10, engineering plastic for industrial applications in the area of automobile, textile, and information and communications technologies (ICT). In this presentation, we report development of recombinant Escherichia coli strains expressing different kinds of LDCs derived from various microbial sources for the high-level conversion of L-lysine into cadaverine. Detailed results will be presented.  
Acknowledgements-This work was supported by Industrial Strategic Technology Development Program (10047910, Production of biobased cadaverine and polymerization of Bio-polyamide 510) funded by the Ministry of Trade, Industry & Energy (MOTEI, Korea)
저자 박시재1, 최재우2, 강경희2, 권미정1, 장영아2, 오영훈2, 김일권3, 박경문4, 송봉근2, 이승환5
소속 1명지대, 2한국화학(연), 3백광산업, 4홍익대, 5전남대
키워드 lysine; cadaverine; E. coli
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