The article describes results of investigations of heat transfer and pressure drop during saturated bubbly boiling of new environment-friendly refrigerating media. Taking advantage of the experimental results, an analytical model of heat transfer and pressure drop is worked out. An essential feature of the model is that it accounts for components of the heat flux density in the boundary sublayer due to convection, interaction of heat sinks, and turbulence effects. The comparison of computational results and experimental data, from the present study and from other investigations, shows that the proposed method of determination of heat transfer coefficients and pressure drop can be applied to a number of refrigerating media with a wide range of heat and flow parameters, assuring accuracy to +/-20%. Therefore, the method can be used in design of heat exchangers for refrigeration units as well as complete refrigeration units.