International Journal of Molecular Sciences, Vol.13, No.6, 7508-7520, 2012
The Effect of Toll-Like Receptor 4 on Macrophage Cytokines During Endotoxin Induced Uveitis
Toll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 in vivo during EIU than normal. In this study, we analyzed levels of peritoneal macrophage cytokines from C3H/HeN mice with LPS stimulation in vitro to elucidate the effect of TLR4 on cytokines during EIU.