In this study, substoichiometric titanium oxide, TinO2n-1, was compared with carbon black and TiO2 in the role of catalyst supports for Pd in alkaline direct ethanol fuel cell. 10%Pd/C, 10% Pd/commercial TiO2 and 10%Pd/TinO2n-1, catalysts were successfully prepared by a polyol method. The supports and electrocatalysts were characterized by X-ray diffraction (XRD), nitrogen adsorption, electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), linear sweep voltammetry (LSV), and chronoamperometry (CA) techniques. Excellent durability was found for TinO2n-1 with holding potential and multiscan tests in N-2-purged 1 M KOH solution. Among the three catalysts, Pd/TinO2n-1, showed the best activity and stability for ethanol electrooxidation in alkaline media.