Solvent deasphalting process is an important technology for upgrading heavy oil available in the petroleum processing industry today. The state-of-the-art deasphalting process extracts quality deasphalted oil and deoils asphalt from atmospheric or vacuum residuum and other heavy feedstock to offer qualified feedstock for downstream. To integrate the solvent deasphalting process with the fluid catalytic cracking process may bring solvent deasphalting into full play. This work presents deasphalting characteristics of modified vacuum residuum by fluid catalytic cracking slurry oil using propane as the solvent. One of the objectives is to improve the quality of deoiled asphalt by the use of polynuclear aromatics rich in fluid catalytic cracking slurry oil to avoid its pavement troubles; and the other objective is to provide experimental data for the solvent deasphalting process integrating with fluid catalytic cracking unit. Deasphalting experiments are carried out in a pilot scale unit and catalytic cracking experiment of deasphalted oil is completed in MRCS-8006 heavy oil micro-reaction equipment. The experimental results show that when vacuum residuum modified by fluid catalytic cracking slurry oil is used as the feedstock of solvent deasphalting, not only the deasphalted oil yield can be increased, but also the asphaltic by-product may be directly used as a suitable grade pavement pitch.