In the thermal-catalytic steam-cracking (TCSC) of "naphtha-methanol" mixtures, the increasing presence of methanol in the feed significantly modified the kinetics of the catalytic cracking. The gradual and significant decrease of the apparent activation energy with increasing methanol concentration in the mixed feed was attributed to the effect of intensive interactions between the two types of molecules: hydrocarbons and methanol. The addition of methanol into petroleum naphtha feed, up to 25 wt%, did not significantly change the catalytic performance of the TCSC hybrid nano-catalyst, suggesting that this catalyst could create at such relatively low methanol concentrations, a certain compatibility between the feed components.