To investigate the influence of the organosilicon-acrylic on wetting properties of porous media, contact angle tests were performed on two different sandstones. In addition, the effectiveness of the emulsion on wettability alteration of porous media was validated by capillary rise and spontaneous imbibition tests. The results of wettability tests showed that the wettability of two sandstones was altered from water-wet to gas-wet after treatment with the emulsion. The principle that the critical radius of pore throats and wettability of porous media affect liquids flow was derived analytically and verified experimentally. Coreflood results demonstrated that the latex resulted in increasing the water permeability through altering the rock wettability to gas-wetting, then decreasing the friction drag between liquids and rocks surface. Thereby, the emulsion treatment could increase the flowback rate of trapped liquids. Experimental results were in good agreement with the theoretical analysis. In conclusion, all results indicated that the emulsion could alter the wettability from water-wet to intermediate gas-wet and enhance water permeability in porous media. It was extrapolated that the emulsion had the tremendous potential to be applied in field conditions, enhancing gas productivity through the cleanup of trapped water in the vicinity of the wellbore.