We present a joint experimental and theoretical study on metal dusting phenomena in Ni binary alloys containing group-13, 14, and 15 elements in the periodic series. Laboratory metal dusting test of several Ni binary alloys was conducted in a simulated syngas atmosphere consisting of CO, H(2), CO(2), and H(2)O at 923 K for 100 h. The Ni alloys containing the group-14 and 15 elements exhibited excellent metal dusting resistance, while those containing the group-13 did not. This behavior is reasonably interpreted from the Blyholder mechanism and the electron filling concept in the p-d hybridization states for the associated alloys. (C) 2011 The Electrochemical Society. [DOI: 10.1149/2.014112jes]