화학공학소재연구정보센터
Journal of Bioscience and Bioengineering, Vol.113, No.1, 73-75, 2012
Efficient production of L-lactic acid from xylose by a recombinant Candida utilis strain
Efficient L-lactic acid production from xylose was achieved using a pyruvate decarboxylase-deficient Candida utilis strain expressing an L-lactate dehydrogenase, an NADH-preferring mutated xylose reductase (XR), a xylitol dehydrogenase and a xylulokinase. The recombinant strain showed 53% increased L-lactic acid production compared with the reference strain expressing native XR (NADPH-preferring). (C) 2011, The Society for Biotechnology, Japan. All rights reserved.