This article deals with the influence of heat and mass transfer on peristaltic flow of a hyperbolic tangent fluid in an annulus. The two dimensional equations of tangent hyperbolic fluid are simplified by making the assumptions of long wave length and low Reynolds number. Exact solutions are evaluated for both heat and concentration field, while analytical and numerical solutions are carried out for velocity profile. Comparison of both the solution is presented through graph and table. The expressions for pressure rise, temperature, concentration field and pressure gradient are sketched for various embedded parameters and interpreted. (C) 2011 Elsevier Ltd. All rights reserved.