The influence of technological parameters on dehydrochlorination of dichloropropanols to epichlorohydrin performed on a reaction-stripping column and a prereactor was studied. For a fixed flows of dichloropropanols solution, lime milk solution, and steam through the column, the conversion of dichloropropanols and the yield of epichlorohydrin were calculated. The influence of an excess of lime milk solution, recirculation of the water layer of the distillate from the column, the rate of steam flow through the column, and an excess of calcium hydroxide over dichloropropanols on the course of the process was studied. Moreover, the effects of the reaction time and temperature of the prereactor were tested.