In this work, the group contribution (GC) method is coupled with the least-squares support vector machine (LSSVM): mathematical algorithm to develop a model for representation/prediction of the dissociation conditions of structure H (sH) clathrate hydrates Of methane with 21 hydrocarbon promoters namely as Water "insoluble" promoters. Almost all of available literature data are studied to present a reliable model validated the following statistical parameters: absolute average relative deviations (AARD) of the represented/predicted dissociation pressures from the reported experimental values: about 1.6%, and squared Correlation coefficient 0.99.