The present article demonstrates the synthesis of p-tetraaminocalix[4]arene- and p-tetrathioureacalix[4] arene-based resins (4 and 5). The resins (4 and 5) were characterized by using different analytical techniques such as FT-IR and elemental analysis. In addition, their comparative fluoride sorption study was conducted and it was observed that 5 is highly efficient for the removal of fluoride from aqueous media at a wide range of pH as compared to 4. Consequently, on the basis of kinetic and thermodynamic studies, the pseudo first-order, pseudo second-order, entropy, enthalpy, and Gibbs free energy of fluoride sorption onto resin 5 were calculated. The experimental data were also evaluated by equations of isotherms used, i.e., Freundlich, Langmuir. and Dubinin-Radushkevich. The observations reveal that the sorption is favorable and confer the physiosorption interaction between resin 5 and fluoride. (C) 2011 Elsevier B.V. All rights reserved.