Journal of Industrial and Engineering Chemistry, Vol.18, No.1, 321-324, January, 2012
Temperature-sensitive hydrogel prepared by graft polymerization of N-isopropylacrylamide onto macroradical Pluronic
E-mail:
A new series of thermo-responsive graft copolymers were prepared via consecutive Pluronic backboneinitiated by t-butylperoxybenzoate with N-isopropylacrylamide (NIPAAm) onto Pluronic by a radicalinduced graft polymerization technique. The thermal characterizations of the graft copolymers were investigated by differential scanning calorimetry (DSC). The Pluronic-g-poly(NIPAAm) copolymers exhibited sol-to-gel transitions depending on chain length of the grafted poly(NIPAAm) onto Pluronic. The graft copolymers indicated that the hydrophobic-hydrophilic balance achieved by varying contents of NIPAAm was an important parameter in controlling the transition temperature of the graft copolymers in solution and stability of the resultant gels. The data suggest that graft copolymers may be attractive substrates for tissue engineering and drug delivery applications as the combination of mechanistically independent gelation techniques with regard to gelation kinetics.
- Choi GJ, J. Ind. Eng. Chem., 3(3), 223 (1997)
- Zhang XQ, Li JG, Li W, Zhang A, Biomacromolecules, 8(11), 3557 (2007)
- Yang HS, Kwon OH, Lee JD, Kang PH, J. Ind. Eng. Chem., 2(2), 106 (1996)
- Censi R, Fieten PJ, di Martino P, Hennink WE, Vermonden T, Macromolecules, 43(13), 5771 (2010)
- Baroli B, J. Pharm. Sci., 96, 2197 (2007)
- Hong YJ, Lee HY, Kim JC, J. Ind. Eng. Chem., 15(5), 758 (2009)
- Lee Y, Park SY, Kim C, Park TG, J. Controlled Release., 135, 89 (2009)
- Lee Y, Park SY, Park TG, J. Nanosci. Nanotechnol., 8, 5236 (2008)
- Park SY, Chung HJ, Lee Y, Park TG, J. Biotechnol., ., 669 (2008)
- Lee Y, Park SY, Mok H, Park TG, Bioconjugate Chem., 19, 525 (2008)
- Park SY, Lee Y, Bae KH, Ahn CH, Park TG, Macromol. Rapid Commun., 28(10), 1172 (2007)
- Bromberg L, J. Phys. Chem. B, 102(11), 1956 (1998)
- Zhang Y, Lam YM, J. Colloid Interface Sci., 306(2), 398 (2007)
- Zhu YT, An LJ, Jiang W, Macromolecules, 36(10), 3714 (2003)
- Mele´ndez-Ortiz HI, Bucio E, Burillo G, Radiat. J. Phys. Chem., 1, 78 (2009)
- Campos PGS, Fantini MCA, Petri DFS, J. Braz. Chem. Soc., 15, 532 (2004)
- Zhang Y, Lam YM, J. Colloid Interface Sci., 285(1), 80 (2005)
- Kim SJ, Lee CK, Lee YM, Lee KB, Park YD, Kim SI, J. Appl. Polym. Sci., 90(14), 3922 (2003)
- Lin HH, Cheng YL, Macromolecules, 34(11), 3710 (2001)
- Zhang XZ, Chu CC, J. Appl. Polym. Sci., 89(7), 1935 (2003)
- Park SY, J. Ind. Eng. Chem., 16(4), 560 (2010)
- Hu JM, Ge ZS, Zhou YM, Zhang YF, Liu SY, Macromolecules, 43(12), 5184 (2010)
- Jeong B, Kim SW, Bae YH, Adv. Drug Delivery Rev., 54, 37 (2002)
- Eom GT, Oh SY, Park TG, J. Appl. Polym. Sci., 70(10), 1947 (1998)
- Wang Q, Xu HB, Yang XL, Yang YJ, Polym. Eng. Sci., 49(1), 177 (2009)
- Lee BH, Vernon B, Macromol. Biosci., 5, 629 (2005)
- Recillas M, Silva LL, Peniche C, Goycoolea FM, Rinaudo M, Arguelles-Monal WM, Biomacromolecules, 10(6), 1633 (2009)
- Zhou J, Wang GN, Zou L, Tang LP, Marquez M, Hu ZB, Biomacromolecules, 9(1), 142 (2008)
- Zhang ZK, Krishna N, Lettinga MP, Vermant J, Grelet E, Langmuir, 25(4), 2437 (2009)
- Stile RA, Burghardt WR, Healy KE, Macromolecules, 32(22), 7370 (1999)
- Garbern JC, Hoffman AS, Stayton PS, Biomacromolecules, 11(7), 1833 (2010)
- Wang ZC, Xu XD, Chen CS, Yun L, Song JC, ACS Appl. Mater. Interfaces., 2, 1009 (2010)
- Cheng V, Lee BH, Pauken C, Vernon BL, J. Appl. Polym. Sci., 106(2), 1201 (2007)
- Robb SA, Lee BH, McLemore R, Vernon BL, Biomacromolecules, 8(7), 2294 (2007)
- Lee BH, West B, McLemore R, Pauken C, Vernon BL, Biomacromolecules, 7(6), 2059 (2006)
- Zhang JX, Qiu LY, Jin Y, Zhu KJ, J. Biomed. Mater. Res., Part B., 76A, 773 (2005)