Fabrication of An Antibacterial Non-Woven Mat of a Poly(lactic acid)/Chitosan Blend by Electrospinning

Hang Thi Au; Lan Ngoc Pham; Thu Ha Thi Vu; Jun Seo Park

Macromolecular Research, Vol.20, No.1, 51-58, January, 2012

DOI10.1007/s13233-012-0010-9 Export Citation

Fabrication of An Antibacterial Non-Woven Mat of a Poly(lactic acid)/Chitosan Blend by Electrospinning

Hang Thi Au, Lan Ngoc Pham¹, Thu Ha Thi Vu², and Jun Seo Park^†

Division of Chemical Engineering, Hankyong National University, Gyeonggi, 456-749, Korea
¹Faculty of Chemistry, Hanoi University of Science, Hanoi, Vietnam, Korea
²Vietnam Institute of Industrial Chemistry, Hanoi, Vietnam, Korea

E-mail:

Nonwoven mats made of a poly(lactic acid)/chitosan (PLA/CS) blend and a PLA/CS blend containing silver (Ag) nanoparticles (Ag/PLA/CS) were prepared using an electrospinning technique. The morphology of electrospun fibers was observed by field emission scanning electron microscopy. The addition of AgNO3 to the PLA/CS blend solution improved the electrospinning ability of the PLA/CS blend. The average diameters of the electrospun PLA/CS and Ag/PLA/CS blend fibers decreased as CS content increased. The Ag particles were evenly distributed in PLA/CS ultrafine fibers observed under transmission electron microscopy. Ag nanoparticles were spontaneously generated during the electrospinning process. When the CS content in the blend increased, the size of the Ag nanoparticles on the surface of the electrospun fibers increased as well. The thermal and mechanical properties of the nonwoven mats were examined by differential scanning calorimetry and a tensile tester. Fourier transform infrared spectroscopy was used to characterize the molecular interactions among PLA, Ag, and CS in the blends. The antibacterial activity of the nonwoven mats against Escherichia coli and Staphylococcus aureus was studied using an optical density method.

Keywords:chitosan;poly(lactic acid);silver nanoparticles;antibacterial activity;electrospinning.

[References]

Xu J, Zhang J, Gao W, Liang H, Wang H, Li J, Mater. Lett., 63, 658 (2009)
Ignatova M, Starbova K, Markova N, Manolova N, Rashkov I, Carbohydr. Res., 341, 2098 (2006)
Torres-Giner S, Ocio M, Lagaron J, Eng. Life Sci., 8, 303 (2008)
Son WK, Youk JH, Park WH, Carbohydr. Polym., 65, 430 (2006)
Wei D, Sun W, Qian W, Ye Y, Ma X, Carbohydr. Res., 344, 2375 (2009)
Natarajan KGGV, Han SS, Nahm KS, Lee YS, Iran. Polym. J., 18, 383 (2009)
Jin WJ, Jeon HJ, Kim JH, Youk JH, Synth. Met., 157, 454 (2007)
Chen C, Dong L, Cheung MK, Eur. Polym. J., 41, 958 (2005)
Park WH, Jeong L, Yoo DI, Hudson S, Polymer, 45(21), 7151 (2004)
Torres-Giner S, Ocio MJ, Lagaron JM, Carbohydr.Polym., 77, 261 (2009)
Jia YT, Gong J, Gu XH, Kim HY, Dong J, Shen XY, Carbohydr. Polym., 67, 403 (2007)
An J, Zhang H, Zhang J, Zhao Y, Yuan X, Colloid Polym. Sci., 287, 1425 (2009)
Yang SL, Wu ZH, Yang W, Yang MB, Polym. Test., 27, 957 (2008)
Suyatma N, Copinet A, Tighzert L, Coma V, J. Polym.Environ., 12, 1 (2004)
Tsuji H, Mizuno A, Ikada Y, J. Appl. Polym. Sci., 77(7), 1452 (2000)
Zhang XF, Hua H, Shen XY, Yang Q, Polymer, 48(4), 1005 (2007)
Sebastien F, Stephane G, Copinet A, Coma V, Carbohydr.Polym., 65, 185 (2006)
Peesan M, Supaphol P, Rujiravanit R, Carbohydr.Polym., 60, 343 (2005)
Zong XH, Kim K, Fang DF, Ran SF, Hsiao BS, Chu B, Polymer, 43(16), 4403 (2002)
Kim ES, Kim SH, Lee CH, Macromol. Res., 18(3), 215 (2010)
Hong KH, Park JL, Sul IH, Youk JH, Kang TJ, J. Polym. Sci. B: Polym. Phys., 44(17), 2468 (2006)
Ye WP, Du FS, Jin JY, Yang JY, Xu Y, React. Funct. Polym., 32(2), 161 (1997)
van de Witte P, Dijkstra PJ, van den Berg JWA, Feijen J, Polym. Phys., 34, 2553 (1996)
Fang L, Qi R, Liu L, Juan G, Huang S, Int. J. Polym.Sci., 2009, 7 (2009)
Mark EJ, Polymer Data Handbook, Oxford University Press, New York (1998)
Li Z, Zhuang XP, Liu XF, Guan YL, De Yao K, Polymer, 43(4), 1541 (2002)
Tran HV, Tran LD, Ba CT, Vu HD, Nguyen TN, Pham DG, Nguyen PX, Colloids Surf. A: Physicochem. Eng. Asp., 360, 32 (2010)
Sajeev US, Anand KA, Menon D, Nair S, Bull.Mater. Sci., 31, 343 (2008)
Sakurai K, Maegawa T, Takahashi T, Polymer, 41(19), 7051 (2000)
Shuai X, He Y, Asakawa N, Inoue Y, J. Appl. Polym. Sci., 81(3), 762 (2001)
Suyatma NE, Copinet A, Tighzert L, Coma V, J.Polym. Environ., 12, 1 (2004)
Son B, Yeom BY, Song SH, Lee CS, Hwang TS, J. Appl. Polym. Sci., 111(6), 2892 (2009)

[Referenced By]

[1] Xu J, Zhang J, Gao W, Liang H, Wang H, Li J, Mater. Lett., 63, 658 (2009)

[2] Ignatova M, Starbova K, Markova N, Manolova N, Rashkov I, Carbohydr. Res., 341, 2098 (2006)

[3] Torres-Giner S, Ocio M, Lagaron J, Eng. Life Sci., 8, 303 (2008)

[4] Son WK, Youk JH, Park WH, Carbohydr. Polym., 65, 430 (2006)

[5] Wei D, Sun W, Qian W, Ye Y, Ma X, Carbohydr. Res., 344, 2375 (2009)

[6] Natarajan KGGV, Han SS, Nahm KS, Lee YS, Iran. Polym. J., 18, 383 (2009)

[7] Jin WJ, Jeon HJ, Kim JH, Youk JH, Synth. Met., 157, 454 (2007)

[8] Chen C, Dong L, Cheung MK, Eur. Polym. J., 41, 958 (2005)

[9] Park WH, Jeong L, Yoo DI, Hudson S, Polymer, 45(21), 7151 (2004)

[10] Torres-Giner S, Ocio MJ, Lagaron JM, Carbohydr.Polym., 77, 261 (2009)

[11] Jia YT, Gong J, Gu XH, Kim HY, Dong J, Shen XY, Carbohydr. Polym., 67, 403 (2007)

[12] An J, Zhang H, Zhang J, Zhao Y, Yuan X, Colloid Polym. Sci., 287, 1425 (2009)

[13] Yang SL, Wu ZH, Yang W, Yang MB, Polym. Test., 27, 957 (2008)

[14] Suyatma N, Copinet A, Tighzert L, Coma V, J. Polym.Environ., 12, 1 (2004)

[15] Tsuji H, Mizuno A, Ikada Y, J. Appl. Polym. Sci., 77(7), 1452 (2000)

[16] Zhang XF, Hua H, Shen XY, Yang Q, Polymer, 48(4), 1005 (2007)

[17] Sebastien F, Stephane G, Copinet A, Coma V, Carbohydr.Polym., 65, 185 (2006)

[18] Peesan M, Supaphol P, Rujiravanit R, Carbohydr.Polym., 60, 343 (2005)

[19] Zong XH, Kim K, Fang DF, Ran SF, Hsiao BS, Chu B, Polymer, 43(16), 4403 (2002)

[20] Kim ES, Kim SH, Lee CH, Macromol. Res., 18(3), 215 (2010)

[21] Hong KH, Park JL, Sul IH, Youk JH, Kang TJ, J. Polym. Sci. B: Polym. Phys., 44(17), 2468 (2006)

[22] Ye WP, Du FS, Jin JY, Yang JY, Xu Y, React. Funct. Polym., 32(2), 161 (1997)

[23] van de Witte P, Dijkstra PJ, van den Berg JWA, Feijen J, Polym. Phys., 34, 2553 (1996)

[24] Fang L, Qi R, Liu L, Juan G, Huang S, Int. J. Polym.Sci., 2009, 7 (2009)

[25] Mark EJ, Polymer Data Handbook, Oxford University Press, New York (1998)

[26] Li Z, Zhuang XP, Liu XF, Guan YL, De Yao K, Polymer, 43(4), 1541 (2002)

[27] Tran HV, Tran LD, Ba CT, Vu HD, Nguyen TN, Pham DG, Nguyen PX, Colloids Surf. A: Physicochem. Eng. Asp., 360, 32 (2010)

[28] Sajeev US, Anand KA, Menon D, Nair S, Bull.Mater. Sci., 31, 343 (2008)

[29] Sakurai K, Maegawa T, Takahashi T, Polymer, 41(19), 7051 (2000)

[30] Shuai X, He Y, Asakawa N, Inoue Y, J. Appl. Polym. Sci., 81(3), 762 (2001)

[31] Suyatma NE, Copinet A, Tighzert L, Coma V, J.Polym. Environ., 12, 1 (2004)

[32] Son B, Yeom BY, Song SH, Lee CS, Hwang TS, J. Appl. Polym. Sci., 111(6), 2892 (2009)