During the recent decade, microreaction technologies became an established technique for research and development purposes as well as industrial production. The superior advantages in terms of process intensification by enhanced heat and mass transfer as well as process control and safety issues lead to a growing need for scientists with microreaction technology experiences. The pressure loss and energy dissipation of fluids flowing in microdevices are the most important procedural basis. Pressure loss effects have to be taken into account for the layout of microsystems as well as the assembly of different microfluidic devices. Furthermore, the pressure loss is a quite sensitive parameter for changes in the hydrodynamic diameter of the used microdevices which may vary by production tolerances or fouling processes. Here, some educational experiments for experimental teaching of basic pressure loss principles in microdevices are presented.