Slide coating is one of the pre-metered methods used for high precision single and multilayer coatings. The thickness of each liquid layers is set by the flow rate and web speed only and it is independent of other process parameters. The uniformity of the deposited layer, however, is affected by the operating conditions. In the design of coating processes, it is crucial to know the set of conditions at which the deposited layer is adequately uniform, i.e. to define the operability window of the process. We developed a theoretical model of slide coating flow by solving the full two-dimensional Navier-Stokes equations and used it to uncover the mechanisms of coating bead breakdown at low vacuum, high vacuum, and low flow limits. With full understanding of the bead breakup processes, we then constructed a theoretical coating window as a function of coating thickness, web speed, and applied vacuum. A simple stability criterion was used to predict the onset of ribbing instability and deployed to add the onset of ribbing limit inside the coating window. (C) 2011 Elsevier Ltd. All rights reserved.