Experiments of high-pressure dense-phase pneumatic conveying of pulverized coal with different mean particle sizes using nitrogen were carried out in an experimental test facility with a conveying pressure of up to 4MPa. The effects of three representative operating parameters (solids-to-gas mass flow ratio, conveying pressure, mean particle size) on the total pressure drop were examined. The pressure drops across the horizontal and vertical bends were analyzed by experimental and analytical calculation. The results show that the pressure drop due to gas friction is of much less significance, while the pressure drop due to the solids friction component of the total pressure drop dominates. There exists a relationship between the pressure drop due to solids kinetic energy loss and mass flux of solids.