A novel kind of TEM support composed of graphene oxide monolayers was fabricated by a facile solution-cast method. Compared to the conventional carbon supporting films, such graphene oxide film ( GO-film) performed better stability under high-energy electron beams and better dispersion effect for water-soluble nanoparticles. Quantitative improvement in TEM imaging resolution for nanomaterials on such GO-films compared to the commercial ultrathin carbon films was demonstrated. (C) 2011 Elsevier B. V. All rights reserved.