Preparation and Characterizations of Anisotropic Chitosan Nanofibers via Electrospinning

R. Nirmala; Baek Woo Il; R. Navamathavan; Mohamed H. El-Newehy; Hak Yong Kim

Macromolecular Research, Vol.19, No.4, 345-350, April, 2011

DOI10.1007/s13233-011-0402-2 Export Citation

Preparation and Characterizations of Anisotropic Chitosan Nanofibers via Electrospinning

R. Nirmala¹, Baek Woo Il², R. Navamathavan³, Mohamed H. El-Newehy⁴, and Hak Yong Kim^{2, 4, †}

¹Bio-nano System Engineering, College of Engineering, Chonbuk National University, Jeonju, 561-756, Korea
²Department of Textile Engineering, Chonbuk National University, Jeonju, 561-756, Korea
³School of Advanced Materials Engineering, Chonbuk National University, Jeonju, 561-756, Korea
⁴Petrochemical Research Chair, Department of Chemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia

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We report the preparation of anisotropic chitosan nanofibers prepared using an electrospinning technique. The effect of electrospinning on the formation of nanofibers was examined from results of bulk chitosan. The morphological, structural characterizations and thermal properties of the chitosan bulk and electrospun nanofibers were analyzed by field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetry (TGA), Fourier transform infrared (FTIR), and Raman spectroscopy. Matrixassisted laser desorption ionization time-of-flight (MALDI-TOF) was performed to accurately characterize the high aspect ratio nanofiber structure by the direct identification of mass resolved chains. FE-SEM showed that the electrospun chitosan nanofibers had diameters ranging from 10 to 1,200 nm with an anisotropic nature. MALDI-TOF revealed the presence of lower mass group protonated amino groups, which was the main constituent for the formation of the ultrafine nanofibers in chitosan.

Keywords:electrospinning;chitosan;anisotropic;nanofibers;structure.

[References]

Suh JK, Matthew HWT, Biomaterials, 21, 2589 (2000)
Borchard G, Adv. Drug Deliv. Rev., 52, 145 (2001)
Tomihata K, Ikada Y, Biomaterials, 18, 567 (1997)
De Vrieze S, Westbroek P, Van Camp T, Van Langenhove L, J. Mater. Sci., 42(19), 8029 (2007)
Matsuda A, Kagata G, Kino R, Tanaka J, J. Nanosci. Nanotechnol., 7, 852 (2007)
Kim HS, Kim JT, Jung YJ, Ryu SC, Son HJ, Kim YG, Macromol. Res., 15(1), 65 (2007)
Reneker DH, Chun I, Nanotechnology, 7, 216 (1996)
Kenawy ER, Bowlin GL, Mansfield K, Layman J, Simpson DG, Sanders EH, Wnek GE, J. Control. Release, 81, 57 (2002)
Li D, Wang Y, Xia Y, Nano Lett., 3, 1167 (2003)
Schiffman JD, Schauer CL, Biomacromolecules, 8(2), 594 (2007)
Martinova L, Lubasova D, RJTA, 12, 72 (2008)
Ojha SS, Stevens DR, Hoffman TJ, Stano K, Klossner R, Scott MC, Krause W, Clarke LI, Gorga RE, Biomacromolecules, 9(9), 2523 (2008)
Jia YT, Gong J, Gu XH, Kim HY, Dong J, Shen XY, Carbohydr. Polym., 67, 403 (2007)
Ma Y, Zhou T, Zhao C, Carbohydr. Polym., 343, 230 (2008)
Shalumon KT, Aunlekha KH, Girish CM, Prasanth R, Nair SV, Jayakumar R, Carbohydr. Polym., 10.1016/j.carbpol.2009.11.039
Geng X, Kwon OH, Jang J, Biomaterials, 26, 5427 (2005)
Min BM, Lee SW, Lim JN, You Y, Lee TS, Kang PH, Park WH, Polymer, 45(21), 7137 (2004)
Sarasam AR, Krishnaswamy RK, Madihally SV, Biomacromolecules, 7(4), 1131 (2006)
Allcock HR, Lampe FW, Mark JE, Contemporary Polymer Chemistry, 3rd Ed., Pearson Education, Inc., New Jersey, 2003, p.647.
Sangsanoh P, Supaphol P, Biomacromolecules, 7(10), 2710 (2006)
Garrido IJ, Gonzalez VI, Arechederra JMM, Rienda JMB, Carbohydr. Polym., 68, 173 (2007)
Shigemasa Y, Matsuura H, Sashiwa H, Saimoto H, Int. J. Biol. Macromol., 18, 237 (1996)
Stephens JS, Chase DB, Rabolt JF, Macromolecules, 37(3), 877 (2004)
Liu Y, Cui L, Guan FX, Gao Y, Hedin NE, Zhu L, Fong H, Macromolecules, 40(17), 6283 (2007)

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[3] Tomihata K, Ikada Y, Biomaterials, 18, 567 (1997)

[4] De Vrieze S, Westbroek P, Van Camp T, Van Langenhove L, J. Mater. Sci., 42(19), 8029 (2007)

[5] Matsuda A, Kagata G, Kino R, Tanaka J, J. Nanosci. Nanotechnol., 7, 852 (2007)

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[7] Reneker DH, Chun I, Nanotechnology, 7, 216 (1996)

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[9] Li D, Wang Y, Xia Y, Nano Lett., 3, 1167 (2003)

[10] Schiffman JD, Schauer CL, Biomacromolecules, 8(2), 594 (2007)

[11] Martinova L, Lubasova D, RJTA, 12, 72 (2008)

[12] Ojha SS, Stevens DR, Hoffman TJ, Stano K, Klossner R, Scott MC, Krause W, Clarke LI, Gorga RE, Biomacromolecules, 9(9), 2523 (2008)

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[14] Ma Y, Zhou T, Zhao C, Carbohydr. Polym., 343, 230 (2008)

[15] Shalumon KT, Aunlekha KH, Girish CM, Prasanth R, Nair SV, Jayakumar R, Carbohydr. Polym., 10.1016/j.carbpol.2009.11.039

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[21] Garrido IJ, Gonzalez VI, Arechederra JMM, Rienda JMB, Carbohydr. Polym., 68, 173 (2007)

[22] Shigemasa Y, Matsuura H, Sashiwa H, Saimoto H, Int. J. Biol. Macromol., 18, 237 (1996)

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