The degree of homogeneity and H-bond interaction in blends of low-molecular-mass poly(ethylene glycols) (PEG, M-w = 400, 600, 1000) and poly(vinylpyrrolidone) (PVP, M-w = 9 x 10(3)) prepared in supercritical CO2, ethanol and as physical mixtures were studied by differential scanning calorimetry (DSC), Fourier-transform infrared (FOR) spectroscopy and dynamic mechanical analysis (DMA) techniques. Homogeneity of samples prepared in supercritical CO2 were greater than physically mixed samples, but slightly less than ethanol-cast samples. PEG-PVP H-bond interaction was higher for ethanol-cast blends when compared to blends prepared in supercritical CO2. This reduced interaction was attributed to a combination of: (1) shielding of PEG-PVP H-bond interactions when CO2 is dissolved in the blend; (2) rapidly reduced PEG and PVP chain mobility upon CO2 venting, delaying rearrangement for optimum PEG-PVP H-bond interaction. (C) 2010 Elsevier B.V. All rights reserved.