A process with a power-law model of reaction running in a batch reactor in the presence of catalyst undergoing parallel deactivation has been analyzed. On the basis of the method of variational calculus, a analytical determination aiming at the choice of the optimal temperature condition has been carried out. The advantages resulting from the application to choose the optimal temperature profile with respect to the isothermal conditions in terms of the duration time of the process have been assessed. The effects of the selected kinetic parameter on the magnitude of the above mentioned advantages has also been considered and compared with that obtained for a reaction with deactivation independent of substrate concentration.