A practical quasi three-dimensional numerical model is developed to investigate the heat and mass transfer in a square flat evaporator of a loop heat pipe with a fully saturated wicking structure. The conjugate heat transfer problem is coupled with a detailed mass transfer in the wick structure, and incorporated with the phase change occurring at the liquid-vapor interface. The three-dimensional governing equations for the heat and mass transfer (continuity, Darcy and energy) are developed, with specific attention given to the wick region. By comparing the results of the numerical simulations and the experimental tests, the local heat transfer mechanisms are revealed, through the obtained temperature distribution and the further derived evaporation rates along the liquid-vapor interface. The results indicate that the model developed herein can provide an insight in understanding the thermal characteristics of loop heat pipes during steady-state operation, especially at low heat loads. (C) 2010 Elsevier Ltd. All rights reserved.