An industrial selective hydrogenation process for methylacetylene (MA) and propadiene (PD), consisting of two hydrogenation reactors, a separator drum, and a recycle design, is investigated. Based on the Langmuir-Hinshelwood/Hougen-Watson kinetic model and the on-site plant data, the system identification is accomplished by using nonlinear regression technique. Through dynamic simulation of each reactor, the effect of catalyst deactivation by green oil and the degree of vaporization are verified. To reduce the impurity of C-3-cut stream and improve the catalyst deactivation, the feasible operating manner depends on the determination of H-2/MAPD molar ratios at each reactor and recycle ratio.