Chemistry Letters, Vol.39, No.3, 180-181, 2010
A Straightforward and Efficient Catalyst-free One-pot Synthesis of N-Acyl-1,3-diary1-2-azaphenalene Derivatives via Multicomponent Reactions
A novel, one-pot multicomponent reaction of two molecules of aldehydes with 2,7-naphthalenediol and ammonium carboxylates is described as an efficient and direct procedure for the preparation of N-acy1-1,3-diaryl-2-azaphenalene derivatives in EtOH under reflux conditions. N-Acy1-1,3-diaryl-2-azaphenalene derivatives were obtained in good to high yields without any catalyst or activation.