The effect of grinding media performance on milling and operational behavior is demonstrated for different selected conditions of a water-based red pigment slurry milling. A variety of grinding media materials and bead sizes, along with two different stirrer tip speeds, are used in the grinding process to reduce the particle size in order to increase the color strength of the red pigment. To determine the optimum milling parameters regarding the particle size and the pigment color, the collected test data is used to calculate and evaluate the specific energy and stress intensity under different milling conditions.