Catalysis Letters, Vol.134, No.3-4, 303-308, 2010
Phosphotungstic Acid: An Efficient Catalyst for the Aqueous Phase Synthesis of Bis-(4-hydroxycoumarin-3-yl)methanes
In this present work, we report that phosphotungstic acid provides a simple, efficient and environmentally benign route is a two-component one-pot domino Knoevenagel-type condensation/Michael reaction between 4-coumarin derivative and an aldehyde in water as a solvent in shorter duration with high yields. [GRAPHICS] .