In this study, daily amount of biogas of different mixtures of cheese whey and dairy manure, rates of production of methane, removal efficiencies of chemical oxygen demand (COD), total solid (TS) matter and volatile solid (VS) matter from the mixtures were investigated at 25 and 34 degrees C. In the experimental studies, two different solid matter rates (8% and 10%) were studied. The hydraulic retention times (HRTs) were 5, 10 and 20 days. Removal efficiencies and amount of biogas produced in each HRT were determined. Maximum daily biogas production was obtained as 1.510 m(3) m(-3) d(-1) at HRT of 5 days in the mixture containing 8% total solid matters at 34 degrees C and the methane production rate was around 60 +/- 1% in all experiments. Maximum removal efficiencies for TS, VS and COD were found as 49.5%, 49.4% and 54%, respectively at HRT of 10 days in the mixture containing 8% total solid matters at 34 degrees C. (C) 2010 Elsevier Ltd. All rights reserved.