Nano-sepiolite with novel morphology has been fabricated by solvothermal method in different conditions. The nano-sepiolite was characterized by X-ray fluorescence analysis, X-ray powder diffraction, thermal gravimetry analysis, differential thermal analysis and infrared spectroscopy. Scanning electron microscopy observations revealed that using of solvothermal route led to nano-wires of sepiolite. The reactions have been performed in several conditions to find out the role of different factors such as the aging time and temperature of the reaction in the solvothermal on the size and morphology of the nano-structures. (C) 2009 Elsevier B. V. All rights reserved.