Enthalpies Of dilution of N,N-dirnethylformamide (DMF) in aqueous sucrose and glucose solutions have been determined using an isothermal calorimeter (4400 IMC) at 298.15 K. The values of dilution enthalpy were used to determine homogeneous enthalpic interaction coefficients which characterize the interactions of examined DMF in aqueous sugar solutions. The results show that enthalpic pair interaction coefficients h(2) of DMF are all positive in aqueous sugar solutions and pass through a maximum, respectively, at m approximate to 0.5 mol kg(-1) of sucroseand at m approximate to 0.55 mol kg(-1) of glucose in mixed solvents. In the meantime the h(2) coefficients of DMF in aqueous sucrose solutions are more positive than that in aqueous glucose Solutions. The variations of the enthalpic pairwise interaction coefficients with the mass fraction of sugar in mixtures are interpreted in terms of solute-solute and solute-solvent interactions. (C) 2008 Elsevier B.V. All rights reserved.