A new mixing rule has been developed, which is coupled with a translated and modified version of the Peng-Robinson equation of state (EoS) and the entropic-FV activity coefficient model. The resulting EoS/G(E) model is applied to the correlation and prediction of vapor-liquid equilibria (VLE) in solvent/polymer mixtures, after appropriate modification of the cubic EoS to describe the volumetric behavior of the pure polymer. The model yields very good correlation of experimental equilibrium pressures in concentrated polymer solutions, but more importantly, successful predictions of the same data are obtained. A comparison with other EoS-based models applicable to the prediction of VLE in polymer solutions is also presented.