The catalytic reverse process employs a fixed catalyst bed placed between two beds of noncatalytic material. The gas flow direction in such a "sandwich" is periodically switched from one end to the other. Using a mathematical model of this unsteady-state process, this work discusses the efficiency of the catalytic reverse process for the purification of industrial off-gases containing various volatile organic compounds. A method of process economics optimization is considered. Advantages of the catalytic reverse process in comparison with the traditional steady-state catalytic and regenerative incineration processes of volatile organic compound control are discussed. Potential application of the reverse process and first steps made in this direction by industry are discussed.