We described a cobalt/polypyrrole/carbon nanotube (Co/Ppy/CNT) as non-platinum catalysts for PEMFC. The Co/Ppy/CNT catalyst was characterized by XRD, TEM and XPS. The results showed that polypyrrole was well coated on the surface of CNT and cobalt ion was successfully stabilized on the nitrogen atoms of polypyrrole. The electrocatalytic activity was dependant on thermal treatment conditions. An onset potential of oxygen reduction reaction over Co/Ppy/CNT catalyst increased from 0.55 V to 0.78 V (NHE) after pyrolysis. Therefore, the interaction between cobalt ion and nitrogen atoms and pyrolysis process of catalyst should play and important role to enhance activity of catalyst.