화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.18, No.3, 247-253, March, 2010
DOI10.1007/s13233-010-0301-y  Export Citation
Encapsulation of submicron-sized silica particles by stimuli-responsive copolymer shell layer
M. Abdur Rahman, M. Rabiul Karim, M. A. Jalil Miah, Hasan Ahmad†, and Tsuyoshi Yamashita1
  • Department of Chemistry, Rajshahi University, 6205, Bangladesh
  • 1Nippon Shokubai Co. Ltd., 5-8 Nishi, Otabi-cho, Suita, Osaka, 564-8512, Japan
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This study examined the encapsulation of submicron-sized silica particles by stimuli-responsive copolymer shell layer. Silica/poly(2-dimethylaminoethyl methacrylate-N-isopropylacrylamide-ethyleneglycol dimethacrylate), abbreviated as silica/P(DM-NIPAM-EGDM) core-shell composite polymer particles, were prepared by the seeded copolymerization of DM, NIPAM and EGDM in the presence of silica particles. The morphology and size distribution were analyzed by scanning electron microscopy. The surface composition showed silica particles covered with a copolymer shell layer consisting of P(DM-NIPAM-EGDM). The temperature and pH dependent adsorption behavior of the low molecular weight surfactants and biomolecules on the silica/P(DM-NIPAM-EGDM) composite polymer particles indicated a stimuli-responsive phase transition. The activity of the adsorbed trypsin (TR) on the composite particles remained high compared to the free TR and adsorbed TR on silica particles.
Keywords:silica;temperature- and pH-sensitive;adsorption;specific activity
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