For DNA duplexes, the Lippard laboratory has shown that the XG(star) base pair (bp) step has a very unusual slide and shift, where G(star) is a G platinated at N7 by di- or monofunctional platinum anticancer drugs. One approach toward understanding the cause of this important unexpected XG(star) distortion is to examine single-strand (ss) oligonucleotide (oligo) models. Both duplex and ss XG(star)G(star) models of the key G(star)G(star) cross-link formed by cisplatin have the HH1 conformation with head-to-head bases. Cross-links have R canting (3'-G(star) H8 atom toward 5'-G(star)) in duplexes and L canting (5'-G(star) H8 atom toward 3'-G(star)) in ss models., However, dynamic motion in solution makes the ss features difficult to define. Thus, we employ less dynamic cross-link models such as (R,S,S,R)-BipPt(d(TG(star)G(star))) and (R,S,S,R)-BipPt(d(pG(star)G(star)TTT)), the first examples of an HH1 conformer with R canting for ss oligos longer than d(GpG) (Bip = 2,2'-bipiperidine). In these, the 5'-T residue decreases R canting (indicating steric clashes with the 5'-G(star)) and the less bulky 5'-phosphate group forms a H-bond to HN-Pt (indicating that R canting allows H-bonding). We conclude that the 5'-X residue in duplex adducts changes its position from that in B form DNA to avoid steric clashes with the 5'-G(star) and the carrier ligand and secondarily to form a Watson-Crick base pair. These features, possibly aided by weak carrier-ligand H-bonding, lead to the relatively unusual features distinctive to the "Lippard bp step".