Micellar-enhanced ultrafiltration (MEUF) was used to remove phenol from simulant aqueous solutions. The effect of groups difference of cationic surfactant on the solubilization of phenol was investigated through orthogonal experiment, namely, surfactants with the same length of hydrocarbon chain but different hydrophilic head group and vice versa. The effects on the solubilization of phenol of various operating parameters in the practical application of MEUF with OTAB were studied, including surfactant concentration, electrolyte concentration, feed phenol concentration, operating pressure, temperature, respectively. The results showed that the rejection of phenol increased in the order as follows: cetyltrimethylammonium bromide (CTAB) < octadecyl trimethyl ammonium bromide (OTAB) < cetylpyridinium chloride (CPC). With the introduction of feed surfactant concentration, the retention recovery of phenol increased. Electrolyte concentration, feed phenol concentration, operating pressure and temperature all had a slight influence on the retention of phenol. (C) 2009 Published by Elsevier B.V.