Two sensitive sensors for determination of curcumin (CM) were described. CM can be detected using multiwall carbon nanotube (MWCNT)-modified electrodes and dysprosium nanowire carbon paste electrode using the technique of adsorptive stripping voltammetry (AdSV) in stationary solution and the fast Fourier transform voltammetry at the flowing solution. Both electrodes did show less passivation effect that occurs on the unmodified electrodes and displayed better stability and reproducibility. This electrode enabled selective determination of CM in the presence of interfering species. Under optimized conditions, CM could be detected over a linear range with a detection limit of 5.0 x 10(-9) mol L-1 and 5.0 x 10(-10) mol L-1 for the traditional square wave and fast Fourier transform square wave voltammetry (FFTSWV) with RSD between 0.2 and 0.5%. Comparison with other reported methods showed these studies are about 100 times more sensitive than previous ones. Good selectivity and high sensitivity obtained by Square wave voltammetry can open new possibilities of direct CM determination.