The temperature and pressure profiles of four solvents were simulated at various ultrasonic power levels to suggest models for predicting the energy density. The acousticsmode and heat transfer mode of COMSOL MultiphysicsTM were used to predict the temperature and pressure profiles, respectively. For water, the maximumand minimumpressure at 300Wand 450Wof ultrasonic power level were 8.838 × 10^(6) Pa and -9.533 × 10^(6) Pa, and 1.028 × 10^(7) Pa and -1.1167 × 10^(7) Pa, respectively.The pressure gapwasin the order of water,hexane, methanol and ethanol. For ethanol, themaximumand minimumtemperature of 450Win 1200 s was 337.15 K and 298.25 K, respectively. The energy density of ethanol was the highest among solvents while that of water showed the lowest value. The pressure, temperature and energy density increased with increasing ultrasonic power and irradiation time. The energy density was inversely proportional to temperature, but the cavitation density was in proportion to temperature. The solubility increased with increasing temperature. In overall, the temperature-dependent effect was considered in ultrasound-induced extraction process.