In this paper, we report a facile chemical route to fabricate polymer nanofibers under ambient conditions using aqueous/organic polymerization. The chemical structures of obtained polymers were investigated by infrared spectra and H-1 NMR. Scanning electron microscopy (SEM) observation shows poly[zinc acrylate-co-acrylic poly(ethylene glycol) ester] nanofibers with average diameter 100-140 nm and several micrometers length. A possible mechanism for the formation of polymer nanofibers was investigated.